Center for Network Systems Biology — Boston University

Center for
Network Systems Biology

Physical and functional interactions of biomolecules in diverse complex biological systems that are crucial to health and disease — is an emerging strength at Boston University.

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CNSB Updates

Dear Scientific Research Community at Boston University:         We are

What we do

The Center for Network Systems Biology at Boston University supports ambitious research initiatives to map protein interaction networks in different biomedical contexts. CNSB provides essential interdisciplinary knowledge as well as the technical prowess to get to the heart of network systems biology.
With collaborative research programs based across two Boston University campuses–the BU Medical Campus and the Charles River Campus–the CNSB will serve as a leading hub from which to chart the dynamic molecular networks critical to human cells and tissues.

Our Research

Human health and development depend on dynamic networks of physical, and functional, interactions between proteins. However, the details of these networks – how they are formed and how they function – are largely unknown. More importantly, and perhaps surprisingly, it is still unclear how these networks malfunction in disorders like cancer, neurodegeneration or cardiovascular disease.
With collaborative research programs based across two Boston University campuses–the BU Medical Campus and the Charles River Campus–the CNSB will serve as a leading hub from which to chart the dynamic molecular networks critical to human cells and tissues.

Voices of CNSB

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Human health and development depend on dynamic networks of physical, and functional, interactions between proteins. However, the details of these networks – how they are formed and how they function.

Our Team

A talented team of researchers at the Center is developing and deploying innovative ‘functional proteomic’ methods.
These methods combine protein biochemistry, precision mass spectrometry, and molecular genetics together with integrative statistically-motivated computational approaches to systematically characterize the myriad of protein interactions present inside cells and tissues.