CNSB will generate ground-breaking probabilistic molecular interaction “maps” to define the roles and associations of the many new protein complexes we discover: particular attention will be paid to their functional significance in normal and disease states.
Then, with our many expert biology and clinical partners, members of the Center will perform rigorous, in-depth follow-up mechanistic investigations to validate macromolecules predicted to play key roles in core cellular processes, proper development, and human disease.
As part of its service to the research community, the CNSB will implement outreach and training programs to enable skills uptake by researchers outside of the Center.
Together, the innovative tools, training, and datasets created by the CNSB will serve as valuable resources for the broader scientific community. By drawing together an outstanding team of experts in network biology, systems biology, molecular biology, chemical biology, genomics, and computational modelling, the CNSB aims to create a world class platform for exploring molecular networks and their links to human health and disease.