CNSB Mission
Center for Network Systems Biology

What is Network Systems Biology?

Network systems biology – the study of the physical and functional interactions of biomolecules in diverse complex biological systems that are crucial to health and disease – is an emerging strength at Boston University.

Elucidating the biological networks that drive normal development and pathology is fundamental to a deeper mechanistic understanding of biological processes and their causal links to clinical disorders. Network systems biology is expected to drive biological research in the coming decades.

The CNSB mission is simple: to be a leader in the Boston systems biology community.

Analytical excellence, advanced methods development, and productive partnerships with other leading academic and industry partners form the core ‘identity’ of the Center’s research mandate. To achieve this vision, the Center combines cutting-edge technology, first-class scientific expertise and exceptional training opportunities.

Cutting Edge Technology

By forging a ‘disruptive’ technology platform, the CNSB will be a transformative research enterprise synonymous with scientific excellence, impact and innovation for years to come.

Using state-of-the-art infrastructure, the CNSB will generate global ‘connectivity’ diagrams of cellular protein interactions. In particular, the Center offers exceptional facilities for protein purification, precision mass spectrometry and high-performance computing.

Armed with this array of advanced technology, the CNSB is poised to chart previously uncharacterized interaction networks in both normal and disease states to uncover the molecular basis of essential biological processes, like growth and development.

First-Class Expertise

The research team at CNSB is recognized internationally for their groundbreaking work in Functional Proteomics, Protein Mass Spectrometry and Network Biology. As these areas continue to evolve, the CNSB team are ideally placed to provide global leadership.

The pioneering team includes experts in the generation, analysis and translation of molecular interaction networks to explore fundamental biological processes and disease mechanisms. With outstanding skills in state-of-the-art protein mass spectrometry and other high-throughput techniques, the lab has a prolific research output.

Since 2000, the team has performed >30,000 mass spectrometry experiments and has reported tens of thousands of protein interactions in diverse models, ranging from microbes to human cells, in dozens of high impact papers.

Exceptional Training Opportunities

We are always looking for talented, passionate and dedicated people to join our team. Discover today where you and your bright future fit in with the Emili Group.

We have many interesting genome-scale projects for enthusiastic and enterprising graduate students and postdoctoral fellows (with experience in Biochemistry, Bioanalytical Chemistry, Proteomics/Genomics, and Molecular and Cell Biology), to complement the methods and concepts that you have worked on in your undergraduate and Ph.D. studies, respectively, and to get you on the way with your own productive and successful scientific career.